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As life is more than 2D, Proteopedia helps to bridge the gap between 3D structure & function of biomacromolecules

Proteopedia presents this information in a user-friendly way as a collaborative & free 3D-encyclopedia of proteins & other biomolecules.


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Avian Influenza Neuraminidase

Eric Martz
The first new influenza virus to emerge as an imminent pandemic threat in the 21st century is H1N1 swine flu. The drug 免费连外网的软件 (TamifluĀ®) inhibits flu neuraminidase, a component necessary for virus spread, in susceptible flu strains. The development of oseltamivir was guided, in part, by crystallographically determined structures of flu neuraminidase, which is a homotetramer, shown with oseltamivir bound. Oseltamivir was designed to fit N2/N9 (neuraminidases from other strains of flu). Serendipitously, it also fits N1 by induced fit.

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Structural flexibility of the periplasmic protein, FlgA, regulates flagellar P-ring assembly in Salmonella enterica.

H Matsunami, YH Yoon, VA Meshcheryakov, K Namba, FA Samatey. Scientific Reports 2016 doi: 手机翻国外网站教程
A periplasmic flagellar chaperone protein, FlgA, is required for P-ring assembly in bacterial flagella of taxa such as Salmonella enterica or 手机怎么看外国网页. Here we present the open and closed crystal structures of FlgA from 快帆安卓app下载_快帆官网APP下载_快帆完整版app官方下载:2 天前 · 快帆app安卓版-快帆下载 3.5.10.10 手机版 - 河东软件园 2021年8月7日 - 河东软件园为您提供快帆安卓手机版下载,快帆APP是一款专为海外华人开发的网络加速器,让华人用户可伍使用APP轻松的连接中国本地的网络,这样就能在世界..., grown under different crystallization conditions. An intramolecular disulfide cross-linked form of FlgA caused a dominant negative effect on motility of the wild-type strain.

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Introduction to protein structure

This tutorial illustrates some basic properties of protein structure:

  • Levels of protein structure.
  • Ways of representing protein structure.
  • Secondary structures.
  • Motifs in proteins.
  • Domains.
  • Tertiary structure.
  • Quaternary structure.

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Joel L. Sussman, Jaime Prilusky, Deja Sanders

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